B15

Vitamin B15 A Review and Update

During the past several years, a great furor has arisen over the promotion and sale of pangamic acid also known as Vitamin B15. This was stimulated to some extent by an article in New York magazine (Nobile, 1978) extolling this "vitamin", resulting in near exhaustion of supplies in local retail outlets, a phenomenon which eventually spread to other areas of the country. This article presents so...

Modulation of ionic currents in Aplysia motor neuron B15 by serotonin, neuropeptides, and second messengers.

Both 5-HT and the 9 amino acid neuropeptide SCPb modulate 3 ionic currents in B15, enhancing a voltage-dependent inward sodium current, decreasing an outward potassium current and increasing an inward rectifying potassium current. In contrast, FMRFamide decreases a voltage-dependent inward sodium current and increases an outward potassium current. We have also investigated the roles of several ...

A family case of beta-thalassemia minor and hemoglobin Queens: alpha 34 (B15) Leu-Arg.

We report a Korean family case of beta-thalassemia minor and Hb Queens. This is the first case report of Hb Queens in Korea. A 43-year-old male and his four family members had beta-thalassemia minor which is very rare in Korea. Incidentally, an alpha chain variant with a high isoelectric point was also found in two other family members without clinical problems and was finally identified as alp...

Analysis of HLA-B15 and HLA-B27 in spondyloarthritis with peripheral and axial clinical patterns.

OBJECTIVE Human leucocyte antigen (HLA) B27 and HLA-B15 are associated with spondyloarthritis (SpA). Recent Assessment of SpondyloArthritis international Society (ASAS) criteria emphasise a distinction between SpA with axial and peripheral patterns. We analysed whether HLA-A, HLA-B and HLA-DRB1 alleles could associate with these patterns. METHODS We studied 100 healthy individuals and 178 pat...

Anchored at Their C Termini HLA-B15 Peptide Ligands Are Preferentially